autoimmune diseases
-
In Same Day, UCB Lands Two FDA Drug Approvals in Autoimmune Diseases
FDA approval of UCB’s Bimzelx gives the Belgian drugmaker a contender in the crowded plaque psoriasis therapies market. In the rare disease generalized myasthenia gravis, the agency approved Zilbrysq, a UCB drug with advantages over two blockbuster AstraZeneca drugs addressing the same target.
-
Nektar Sues Eli Lilly, Claiming the Big Pharma Breached Contract to Favor Another Drug
“Botched math” in calculating clinical data for an autoimmune disease drug is one of the allegations Nektar Therapeutics makes in a legal complaint against Eli Lilly. The biotech claims its former partner tried to disadvantage the asset in order to advance development of another drug it acquired in a billion dollar deal.
-
Jorie Healthcare CEO Shares Why Automation is Critical to Revenue Cycle Management
The revenue cycle management business is using AI tools to automate cumbersome tasks to help hospitals operate more efficiently. It’s beginning to attract the attention of major healthcare organizations.
-
Regeneron Jumps Into Cell Therapy via Alliance With Treg Startup Sonoma Bio
Regeneron is paying Sonoma Biotherapeutics $75 million to begin a partnership focused on developing cell therapies based on regulatory T cells, or Tregs. Each company brings technological capabilities to the alliance, which is initially focused on ulcerative colitis and Crohn’s disease.
-
Takeda Details the Clinical Data That Led to a $4B Deal for an Autoimmune Drug
Takeda Pharmaceutical drug TAK-279 achieved the main goal of a mid-stage clinical trial in plaque psoriasis, setting the stage for Phase 3. The Japanese pharmaceutical giant sees the small molecule as complementary to its top-selling product, the blockbuster inflammatory bowel disorder drug Entyvio, and competitive against Bristol Myers Squibb’s Sotyktu.
-
Drug Approvals in 2022: A Recap of Notable FDA Regulatory Decisions
Fewer new drugs won FDA approvals in 2022 compared to previous years, but some of the products that passed regulatory muster are indicative of trends expected to continue into 2023. For example, more gene and cell therapies are on track to face regulatory decisions in the coming year.
-
Gilead Sciences Kicks Off 2023 With New Autoimmune Disease Alliance
Gilead Sciences is building up its autoimmune disease drug pipeline by turning to EVOQ Therapeutics, a startup with technology that takes a novel approach to restoring immune tolerance. For EVOQ, the Gilead deal is its second with a big pharma company.
-
Alpine stops enrollment in cancer drug study after second patient death this year
The second patient who died in the Phase 1 test of Alpine Immune Sciences cancer drug, davoceticept, reportedly suffered the same cardiovascular complication as the first patient. The biotech company is stopping enrollment in two clinical tests of the drug and assessing all participants in the studies.
-
BMS was first but startup Sudo Bio aims to be best at blocking key autoimmune target
Sudo Bioscience emerged with $37 million in funding and four programs that address TYK2, a promising target for autoimmune diseases. Bristol Myers Squibb drug Sotyktu recently won the first FDA approval for a TYK2 inhibitor but Sudo claims its molecules have the potential to be best in this new drug class.
-
FDA approves Roivant drug, the first novel topical plaque psoriasis med in 25 years
Plaque psoriasis drug Vtama is now approved by the FDA, making it the first novel topical treatment for the chronic autoimmune disorder in a generation. Roivant Sciences subsidiary Dermavant Sciences acquired the drug from GlaxoSmithKline in 2018.
-
Navigating Healthcare’s Data Revolution: Priorities, Opportunities, and Challenges for Health Systems
Arcadia recently partnered with HIMSS Market Insights to survey executives, IT, technology, and clinical leaders. Here’s what we found.
-
Flagship merges two of its biotechs to form cellular microenvironment-focused Sonata
Sonata Therapeutics is developing drugs that reprogram cellular microenvironments to send signals intended to have curative effects. Cancer is the initial focus of the biotech, which Flagship Pioneering formed by combining two of its preclinical portfolio companies.
-
Startup Nuvig Therapeutics gets $47M to bring immune system back into balance
Nuvig Therapeutics is developing drugs that tap into one of the body’s natural mechanisms for controlling inflammation. Co-founder and CEO Pamela Conley, a veteran of Portola Pharmaceuticals, says Nuvig’s approach could offer efficacy similar to currently available autoimmune drugs but with a better safety profile.
-
Artificial Intelligence, BioPharma
Seizing “magic moment” for machine learning, startup Seismic unveils $101M
Machine learning is core to the drug research of Seismic Therapeutic, a new biotech startup developing novel drugs for immunology indications. CEO Jo Viney said the company’s initial focus is addressing dysregulation of adaptive immunity.
-
Pfizer: $6.7B Arena buyout complements rather than replaces JAK drugs
Sales of blockbuster Pfizer drug Xeljanz are under pressure from a stronger safety warning placed across that drug’s entire class. In acquiring Arena Pharmaceuticals for $6.7 billion, Pfizer gets a lead compound with a different and potentially safer approach to treating inflammatory conditions.
-
Xilio, Ventyx IPOs raise $269M to fuel plans to compete with big pharma drugs
Cancer drug developer Xilio Therapeutics and Ventyx Biosciences, a company with drug candidates in cancer and autoimmune diseases, are the latest life science companies to go public. They’ll use proceeds from their respective IPOs to continue clinical development of drugs being positioned as competitors to drugs from big pharmaceutical companies.